Hepatorenal Syndrome

Write about Hepatorenal Syndrome here.


HRS occurs in 18% of cirrhotic patients with ascites

• Intense renal vasoconstriction

• Reduced GFR

• Normal renal histology


Treatment = Albumin IV ± heamodialysis


• In cirrhosis, reduced hepatic clearance of immune complexes leads to their trapping in the kidney (therefore -> IgA nephropathy ± hepatic glomerulosclerosis)