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Write about Gut Hormones here. • Cholecystokinin (duodenum and jejunum) - increases gall bladder contraction, increases colonic motility. • Gastrin (antrum and duodenum) - increases gastric acid secretion, increases GI mucosal growth, increases pancreatic secretion indirectly through binding with cholecystokinin. • Secretin (duodenum and jejunum) - increases pancreatic bicarbonate production. • VIP (enteric nerves) - increases intestinal secretion, splanchnic vasodilation. • Pancreatic polypeptide (pancreas) - reduces biliary and pancreatic secretion. • Peptide YY (ileum and colon) - inhibits pancreatic exocrine function. • Neuropeptide Y (enteric nerves) - regulates intestinal blood flow. • Motilin (whole gut) - increases small bowel motility. • Bombesin (gut and pancreas) - stimulates pancreatic exocrine activity. • Somatostatin (stomach and pancreas) - inhibits secretion and action of gut hormones. |
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